New publication from WP3

written by Nadja Železnik
02. Oct 2024
Categories: Papers

A new paper has been published in “Radiation Physics and Chemistry” by colleagues at Karlsruhe Institute of Technology, Germany, working in WP3 of RadoNorm.

In their paper “Application of INTDOSKIT tool for assessment of uncertainties on dose coefficients for ingestion of uranium by workers”, the effectiveness of INTDOSKIT was demonstrated in the R programming language with R studio integrated development environment (IDE) to quantify uncertainties in biokinetic model parameters for the calculation of dose coefficients under defined scenarios of U-238 ingestion by workers. Through an analysis of 60,000 replicates, the study produced dose distributions that highlight the variability in model parameters and show that while the ICRP reference values are generally reliable, they may underestimate average doses and miss extreme cases. The sensitivity analysis identified the fraction of uranium absorbed from the alimentary tract into the blood as a key parameter that contributes to uncertainty hence emphasizing the need for accurate estimation of this parameter. The study supports the robustness of INTDOSKIT and suggests that while ICRP values are useful, the incorporation of additional statistical measures such as higher percentiles or the use of the mean as a reference value could improve radiation protection and dose assessment for U-238 ingestion.

These and more of RadoNorm’s latest publications can be found here.

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